Apolipoprotein E (APOE) Mouse Monoclonal Antibody [Clone ID: E3]

CAT#: AM09106PU-N

Apolipoprotein E (APOE) mouse monoclonal antibody, clone E3, Aff - Purified

Specifications

Product Data

• Clone Name: E3
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot: 1/200 with PBS, pH 7.4 for Immunoblotting (ECL).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human Apolipoprotein E
• Specificity: This antibody reacts with all isoforms E2, E3, E4 of Human Apolipoprotein E (ApoE).
  Detects a 38 kDa band in Western Blotting.
• Formulation: PBS, pH 7.4
  State: Aff - Purified
  State: Lyophilized purified IgG fraction
  Stabilizer: 0.5% BSA
  Preservative: 0.09% Sodium Azide
• Reconstitution Method: Restore in 1 ml distilled water
• Purification: Affinity Chromatography on Protein G
• Storage: Prior to reconstitution store at 2-8°C.
  Following reconstitution store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens apolipoprotein E (APOE), transcript variant 2
• Database Link:
  Entrez Gene 348 Human
• Background: Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition.
• Synonyms: ApoE, Apo-E

Reference Data

• Protein Families: Adult stem cells, Druggable Genome, Secreted Protein, Stem cell - Pluripotency
• Protein Pathways: Alzheimer's disease