Plakophilin 3 (PKP3) Mouse Monoclonal Antibody [Clone ID: PKP3-270.6.2]

CAT#: AM09123SU-N

Plakophilin 3 (PKP3) mouse monoclonal antibody, clone PKP3-270.6.2, Supernatant


USD 310.00

2 Weeks*

Size
    • 5 ml

Product Images

Other products for "PKP3"

Specifications

Product Data
Clone Name PKP3-270.6.2
Applications IF, IHC, WB
Recommended Dilution Immunoblotting: 1/500 ECL method.
Immunofluorescence.
Immunohistochemistry on frozen sections: Ready-to-use.
Reactivities Bovine, Human, Mouse, Xenopus
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant protein (E. coli) of human plakophilin 3
Specificity This antibody reacts to Plakophilin 3.
Positive tissues and culture cells:
- stratified squamous epithelia: palmar, epidermis, scalp skin
- stratified epithelia: tongue, vagina, esophagus
- transitional epithelia: bladder
- non-stratified epithelia: colon, duodenum, pancreas,
several glands
- non-epithelial: reticulum cells of lymph node follicle
- HaCaT, MCF7, HeLa, HT-29, CaCo 2, Caski, BMGE, MDCK and other
Negative tissues and cell lines:
- liver, heart, skeletal muscle, endothelia (vessels)
- PLC, RD, SV80, HL60, Raji, Jok1, Glioma, K562, 3T3L1, A6, PtK2
Formulation State: Supernatant
State: Liquid culture supernatant
Gene Name Homo sapiens plakophilin 3 (PKP3), transcript variant 1
Background Plakophilin 3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalisation, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localisation in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of 87 kD.
Synonyms Plakophilin-3
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.