Cytokeratin 18 (KRT18) (Multi-Epitope Cocktail) Mouse Monoclonal Antibody [Clone ID: Ks18.04/18.27/18.5/9B1/18.174]

CAT#: AM09125SU-N

Cytokeratin 18 (KRT18) (Multi-Epitope Cocktail) mouse monoclonal antibody, clone Ks18.04/18.27/18.5/9B1/18.174, Supernatant


USD 300.00

2 Weeks*

Size
    • 5 ml

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Specifications

Product Data
Clone Name Ks18.04/18.27/18.5/9B1/18.174
Applications IHC, WB
Recommended Dilution Immunoblotting (Western).
Immunohistochemistry on Frozen and paraffin-Embedded Tissue (only when using the microwave method) and Cytological Material.
Working Dilution: Ready-to-use for Immunohistochemistry.
Incubation Time: 1h at RT, extended with paraffin sections (over night at 2-8°C).
Reactivities Bovine, Canine, Fish, Hamster, Human, Mammalian, Mouse, Porcine, Rat, Sheep
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Keratin K18 of Human and Bovine origin.
Specificity The antibody cocktail represents an excellent marker to discriminate simple epithelia from those of different origin.
Tumors Specifically Detected: all adenocarcinoma; mammary carcinoma, urinary bladder carcinoma, undifferentiated carcinoma, cervix carcinoma, hepatocellular carcinoma.
Polypeptide Reacting: Mr 45 000 polypeptide (human and bovine K18; formerly
also designated cytokeratin 18) of all simple type epithelia and basal cells of many squamous, nonepidermal epithelia.
Reactivities on Cultured Cell Lines: HeLa and MCF-7.
Formulation State: Supernatant
State: Hybridoma Culture Supernatant
Preservative: 0.09% Sodium Azide
Storage Store the antibody undiluted at 2-8°C.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens keratin 18, type I (KRT18), transcript variant 1
Background Cytokeratin 18 is an acidic keratin which is found primarily in non-squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas express only Cytokeratins 8 and 18.
Synonyms Cytokeratin-18, CK18, Keratin-18, Keratin 18, KRT18, CYK18, K18
Reference Data
Protein Pathways Pathogenic Escherichia coli infection

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