Desmoplakin (DSP) (2115-2132) Mouse Monoclonal Antibody [Clone ID: DP447]

CAT#: AM09127SU-N

Desmoplakin (DSP) (2115-2132) mouse monoclonal antibody, clone DP447, Supernatant

Specifications

Product Data

• Clone Name: DP447
• Applications: IF, IHC, WB
• Recommended Dilution: Immunoblotting
  Immunofluorescence
  Immunohistochemistry on frozen and Paraffin sections: Ready-to-use, with Paraffin use the microwave retrieval method.
• Reactivities: Bovine, Chicken, Fish, Human, Mouse, Xenopus, Zebrafish
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide of human desmoplakin 2 (aa 2115-2132)
• Specificity: The antibody shows distinct punctate membrane staining of different epithelia. Area compositae of the myocardium of higher vertebrates are also positive. The epitope is located in a region highly conserved among species (human, zebrafish).
  Reacts on several cultured cell lines: Human MCF-7, A-431, HaCaT, CaCo2; Bovine MDBK, BMGE; Rainbow trout RTG-2.
  Polypeptides reacting: Desmoplakin 1 and 2
• Formulation: State: Supernatant
  State: Liquid culture supernatant containing 0.09% sodium azide
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens desmoplakin (DSP), transcript variant 2
• Database Link:
  Entrez Gene 1832 Human
• Synonyms: DP, DSP, 250/210 kDa paraneoplastic pemphigus antigen

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC)