Plakophilin 4 (PKP4) (85-104) Mouse Monoclonal Antibody [Clone ID: 7.7.9 (p0071-1)]

CAT#: AM09132SU-N

Plakophilin 4 (PKP4) (85-104) mouse monoclonal antibody, clone 7.7.9 (p0071-1), Supernatant

Specifications

Product Data

• Clone Name: 7.7.9 (p0071-1)
• Applications: IF, IHC, WB
• Recommended Dilution: Immunoblotting: 1/10-1/50.
  Immunofluorescence: Undiluted.
  Immunohistochemistry on Frozen Sections: Undiluted.
  Immunohistochemistry on Paraffin Sections:
  Incubation Time: 1-1.5 h at RT.
  Positive Control: MCF-7 cells.
• Reactivities: Bovine, Human, Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide of human p0071 (aa position 85-104: EKSFPWRSTDVNTGVSKPR)
• Specificity: This antibody recognizes Plakophilin-4.
  Detects a plaque protein (p0071) specific for a subtype of adherens junctions, with a molecular mass of 135 kD and is closely related to neurojungin / delta-catenin and ARVC (all belonging to the p120 armadillo subfamily). p0071 is specifically detected in the plaques of the composite junctions (area compositae) of cardiac intercalated disks, in puncta adhaerentia of single- and multi-layered epithelia and blood vessel endothelial cells.; it is, however, absent from desmosomes. This protein was also described as plakophilin 4.
  Tested Reactivities on Cultured Cell Lines:MCF-7, A431, CaCo-2, HT-29, PLC, 16HBE14o, HaCaT, SV80,
  U333 CG, 3T3, RVF-SMC, MH1C1.
• Formulation: State: Supernatant
  State: Liquid Hybridoma Culture Supernatant
  Preservative: 0.09% Sodium Azide
• Database Link:
  Entrez Gene 8502 Human
• Background: Plakophilin 4 (PKP4) is an Armadillo-like protein, characterized by a series of armadillo repeats. It is a component of desmosomal plaques and may play a role in junctional plaque organization.
• Synonyms: PKP4, p0071