Interferon gamma (IFNG) Mouse Monoclonal Antibody [Clone ID: 165]
CAT#: AM09168PU-N
Interferon gamma (IFNG) mouse monoclonal antibody, clone 165, Aff - Purified
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Specifications
Product Data | |
Clone Name | 165 |
Applications | ELISA, WB |
Recommended Dilution | ELISA: Reacts with IFN-gamma at 0.1 ng/ml dilution of monoclonal antibody. Western Blot: IFN gamma antibody (AM09168PU-N) used at a concentration of 0.5 µg/ml, will allow visualization of 100 ng/lane of Interferon gamma. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant Human Interferon gamma (IFN gamma). |
Specificity | This antibody recognizes both, recombinant and native human IFN-gamma. |
Formulation | 0.01M PBS, pH 7.0 without preservatives. State: Aff - Purified State: Lyophilized purified IgG fraction. |
Reconstitution Method | Restore with double distillated water is recommended and to adjust the final concentration to 1.00 mg/ml |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein G. |
Conjugation | Unconjugated |
Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens interferon, gamma (IFNG) |
Database Link | |
Background | Mammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2. |
Synonyms | IFN-gamma, gamma IFN |
Note | Myeloma: Sp2/0-Ag14 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Allograft rejection, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Proteasome, Regulation of autophagy, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Type I diabetes mellitus |
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