Interferon gamma (IFNG) Mouse Monoclonal Antibody [Clone ID: 165]

CAT#: AM09168PU-N

Interferon gamma (IFNG) mouse monoclonal antibody, clone 165, Aff - Purified

Specifications

Product Data

• Clone Name: 165
• Applications: ELISA, WB
• Recommended Dilution: ELISA: Reacts with IFN-gamma at 0.1 ng/ml dilution of monoclonal antibody.
  Western Blot: IFN gamma antibody (AM09168PU-N) used at a concentration of 0.5 µg/ml, will allow visualization of 100 ng/lane of Interferon gamma.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant Human Interferon gamma (IFN gamma).
• Specificity: This antibody recognizes both, recombinant and native human IFN-gamma.
• Formulation: 0.01M PBS, pH 7.0 without preservatives.
  State: Aff - Purified
  State: Lyophilized purified IgG fraction.
• Reconstitution Method: Restore with double distillated water is recommended and to adjust the final concentration to 1.00 mg/ml
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G.
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens interferon, gamma (IFNG)
• Database Link:
  Entrez Gene 3458 Human
  UniProt ID P01579
• Background: Mammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2.
• Synonyms: IFN-gamma, gamma IFN
• Note: Myeloma: Sp2/0-Ag14

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Allograft rejection, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Proteasome, Regulation of autophagy, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Type I diabetes mellitus