IL2 Mouse Monoclonal Antibody [Clone ID: 5A8]

CAT#: AM09170PU-N

IL2 mouse monoclonal antibody, clone 5A8, Aff - Purified

Specifications

Product Data

• Clone Name: 5A8
• Applications: ELISA
• Recommended Dilution: ELISA: Clone 5A8 can be used as Detection antibody to detect recombinant Human IL-2 in ELISA when clone 9F9 is used as Capture antibody.
  Clone 5A8 can be reversely used as Capture antibody as well. However it produced better results when used as Detection antibody.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant Human Interleukin-2 (IL2)
• Specificity: Recognizes Interleukin-2.
• Formulation: 0.01M PBS, pH 7.2
  State: Aff - Purified
  State: Lyophilized purified IgG fraction
• Reconstitution Method: Restore with Double distillated water to adjust the final concentration to 1.00 mg/ml
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Upon receipt, store (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens interleukin 2 (IL2)
• Database Link:
  Entrez Gene 3558 Human
  UniProt ID P60568
• Background: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.
• Synonyms: IL-2, TCGF

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus