IL2 Mouse Monoclonal Antibody [Clone ID: 8C2]

CAT#: AM09173PU-N

IL2 mouse monoclonal antibody, clone 8C2, Aff - Purified


USD 540.00

2 Weeks*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name 8C2
Applications ELISA
Recommended Dilution ELISA: Clone 8C2 can detect recombinant Human IL-2.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant Human Interleukin-2 (IL2)
Specificity Reactive to the recombinant Human IL-2.
Formulation 0.01M PBS, pH 7.2 without preservatives.
State: Aff - Purified
State: Lyophilized purified IgG fraction.
Reconstitution Method Restore with double distillated water is recommended to adjust the final concentration to 1.00 mg/ml
Concentration lot specific
Purification Affinity Chromatography on Protein G.
Conjugation Unconjugated
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens interleukin 2 (IL2)
Background Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.
Synonyms IL-2, TCGF
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.