HIV-1 Gag Capsid protein p24 Mouse Monoclonal Antibody [Clone ID: 473]

CAT#: AM09213HR-N

HIV-1 Gag Capsid protein p24 mouse monoclonal antibody, clone 473, HRP

Specifications

Product Data

• Clone Name: 473
• Applications: ELISA, WB
• Recommended Dilution: ELISA: In combination with anti-HIV-1 p24 capture antibody mAb Clone 340 (Cat.-No AM09215PU-N), this HRP conjugated antibody can be used as a tracer antibody for HIV-1 p24 detection in sandwich ELISA.
  Western Blot: 0.1µg/ml.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant HIV-1 P24 (core protein)
• Specificity: This monoclonal antibody reacts with HIV-1 P24 (core protein). No cross activity with HIV-1 GP41 and HIV-2 GP36.
• Formulation: 0.01M PBS, pH 7.0±0.1 in 50% Glycerol
  Label: HRP
  State: Liquid purified IgG fraction
  Label: Horseradish Peroxidase
• Purification: Affinity Chromatography on Protein G
• Conjugation: HRP
• Storage: Upon receipt, store (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Background: HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA.
  Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. P24 is expressed immediately after HIV infection and is detectable before host HIV antibody can be detected. Hence, HIV p24 is currently the target for early diagnosis of HIV acute infection.
• Synonyms: Human immunodeficiency virus type 1, HIV-1 P24, Capsid protein p24