MUC16 Mouse Monoclonal Antibody [Clone ID: 110]

CAT#: AM09240PU-N

MUC16 mouse monoclonal antibody, clone 110, Aff - Purified

Specifications

Product Data

• Clone Name: 110
• Applications: ELISA
• Recommended Dilution: ELISA: Use of this Mucin-16/CA125 antibody at a concentration of 0.125 ng/ml can recognize coated 5 international unit of CA125/well.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human CA125.
• Specificity: React with Human CA125.
• Formulation: 0.01M PBS, pH 7.0 without preservatives.
  State: Aff - Purified
  State: Lyophilized purified Ig fraction.
• Reconstitution Method: Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml.
• Purification: Affinity Chromatography on Protein G.
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  After reconstitution, aliquot and store at -20°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens mucin 16, cell surface associated (MUC16)
• Database Link:
  Entrez Gene 94025 Human
  UniProt ID Q8WXI7
• Background: Mucin16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller subunits being described by some investigators.
• Synonyms: MUC16, MUC-16, CA-125, CA 125