CEACAM5 Mouse Monoclonal Antibody [Clone ID: CEA-Y2]
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Product Data | |
Clone Name | CEA-Y2 |
Applications | ELISA, WB |
Recommended Dilution | ELISA: 1/1000 for CEA Detection with matched pair antibody (Capturer, Cat.-No AM09247PU-N, Clone: CEA-Y1). Western Blot: 25 ng/ml antigen can be detected using 100ng/ml antibody. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human Carcinoembryonic Antigen (CEA). |
Specificity | Recognizes Carcinoembryonic Antigen CEA. Cross-reactivity with other human protein was not found. |
Formulation | 0.01M PBS, pH 7.0 ± 0.1 in 50% Glycerol Label: HRP State: Liquid purified IgG fraction Label: Horseradish Peroxidase |
Purification | Affinity Chromatography on Protein G |
Conjugation | HRP |
Storage | Upon receipt, store (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens carcinoembryonic antigen related cell adhesion molecule 5 (CEACAM5), transcript variant 1 |
Database Link | |
Background | Carcinoembryonic Antigen (CEA) is a 180- 200 kD glycoprotein expressed at high level in the epithelial cells of the embryonic colon. The expression is stopped after birth. CEA serum content is low in normal population and only slightly elevated in heavy smokers. Increased serum CEA level was found to be associated with colorectal carcinoma, gastric carcinoma, pancreatic carcinoma, lung carcinoma, and breast carcinoma. However elevated CEA level does not necessarily indicate neoplastic conditions. CEA level is useful for monitoring tumour recurrence after surgical resection of carcinoma. |
Synonyms | CEA, Carcinoembryonic antigen |
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