CEACAM5 Mouse Monoclonal Antibody [Clone ID: CEA-Y2]

CAT#: AM09248PU-N

CEACAM5 mouse monoclonal antibody, clone CEA-Y2, Aff - Purified

Specifications

Product Data

• Clone Name: CEA-Y2
• Applications: ELISA, WB
• Recommended Dilution: ELISA: The antibody can be used in sandwich ELISA for detection of CEA in combination with matched capture antibody Clone CEA-Y1 (Cat.-No AM09247PU-N).
  Western Blot: 25 ng/lane of antigen can be detected when the antibody was used at 100 ng/ml.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human Carcinoembryonic Antigen (CEA).
• Specificity: Recognizes Carcinoembryonic Antigen CEA. Cross-reactivity with other Human protein was not found.
• Formulation: 0.01M PBS, pH 7.0
  State: Aff - Purified
  State: Lyophilized purified IgG fraction
• Reconstitution Method: Restore with Double distilled water to adjust the final concentration to 1.0 mg/ml.
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Upon receipt, store (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens carcinoembryonic antigen related cell adhesion molecule 5 (CEACAM5), transcript variant 1
• Database Link:
  Entrez Gene 1048 Human
  UniProt ID P06731
• Background: Carcinoembryonic Antigen (CEA) is a 180-200 KD glycoprotein expressed at high level in the epithelial cells of the embryonic colon. The expression is stopped after birth. CEA serum content is low in normal population and only slightly elevated in heavy smokers. Increased serum CEA level was found to be associated with colorectal carcinoma, gastric carcinoma, pancreatic carcinoma, lung carcinoma, and breast carcinoma. However elevated CEA level does not necessarily indicate neoplastic conditions. CEA level is useful for monitoring tumour recurrence after surgical resection of carcinoma.
• Synonyms: CEA, Carcinoembryonic antigen