NSE (ENO2) Mouse Monoclonal Antibody [Clone ID: 1G6]

CAT#: AM09273PU-N

NSE (ENO2) mouse monoclonal antibody, clone 1G6, Aff - Purified

Specifications

Product Data

• Clone Name: 1G6
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Recombinant Human Neuron Specific Enolase (NSE).
• Specificity: Reacts with recombinant Human Neuron Specific Enolase (NSE)
• Formulation: 0.01M PBS, pH 7.2 without preservatives.
  State: Aff - Purified
  State: Lyophilized purified IgG fraction.
• Reconstitution Method: Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml.
• Purification: Affinity Chromatography on Protein G.
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens enolase 2 (gamma, neuronal) (ENO2)
• Database Link:
  Entrez Gene 2026 Human
  UniProt ID P09104
• Background: Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE (neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include pediatric neuroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms.
• Synonyms: NSE, ENO2, Enolase 2,Neural enolase, Gamma-enolase

Reference Data

• Protein Pathways: Glycolysis / Gluconeogenesis, Metabolic pathways, RNA degradation