hCG (CGA) Mouse Monoclonal Antibody [Clone ID: HCG-1]

CAT#: AM09302PU-N

hCG (CGA) mouse monoclonal antibody, clone HCG-1, Aff - Purified

Specifications

Product Data

• Clone Name: HCG-1
• Applications: ELISA
• Recommended Dilution: ELISA: This antibody can be used as capturer in Sandwich ELISA for quantitative determination of HCG in combination with HRP conjugated anti HCG beta subunit antibody (Cat.-No AM09303HR-N).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified Human Chorionic Gonadotropin from urine
• Specificity: This antibody is reactive to Chorionic gonadotropinalpha (hCG-alpha).
• Formulation: 0.01M PBS, pH 7.0
  State: Aff - Purified
  State: Lyophilized purified IgG fraction
• Reconstitution Method: Restore with double distillated water to adjust the final concentration to 1,0 mg/ml
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Upon receipt, store (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens glycoprotein hormones, alpha polypeptide (CGA), transcript variant 2
• Database Link:
  Entrez Gene 1081 Human
  UniProt ID P01215
• Background: Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by placenta after conception. hCG is comprised of a α subunit with 92 amino acids and a β subunit with 245 amino acids. The α subunit is identical to that of LH (Luteinizing hormone), FSH (Follicle-stimulating hormone) and TSH (Thyroid-stimulating hormone). hCG sustains corpus luteum, stimulats progesterone secretion, hence is critical to early foetus development. It has also been reported that hCG plays a role in the development of foetus’s tolerance to maternal immunity. hCG is the most sensitive biomarker for pregnancy.
• Synonyms: Follitropin alpha chain, Follicle-stimulating hormone alpha chain, FSH-alpha, Lutropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, LH alpha, Thyrotropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, hCG-alpha

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
• Protein Pathways: Autoimmune thyroid disease, GnRH signaling pathway, Neuroactive ligand-receptor interaction