Luteinizing Hormone beta (LHB) Mouse Monoclonal Antibody [Clone ID: LH-2]

CAT#: AM09306HR-N

Luteinizing Hormone beta (LHB) mouse monoclonal antibody, clone LH-2, HRP

Specifications

Product Data

• Clone Name: LH-2
• Applications: ELISA
• Recommended Dilution: ELISA: In combination with capture antibody, anti-LH Alpha antibody Clone LH-1 (Cat.-No AM09305PU-N), the antibody can be used for LH detection in sandwich ELISA application.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human LH beta subunit.
• Specificity: This antibody is reactive to beta chain of Luteinizing hormone (LH).
• Formulation: 0.01M PBS, pH 7.2 containing 50% Glycerol
  Label: HRP
  State: Liquid purified IgG fraction
• Purification: Affinity Chromatography on Protein G
• Conjugation: HRP
• Storage: Upon receipt, store (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens luteinizing hormone beta polypeptide (LHB)
• Database Link:
  Entrez Gene 3972 Human
  UniProt ID P01229
• Background: In the female menstrual cycle, during a 24-48 hour period, luteinizing hormone (LH) is rapidly released from gonadotropic cells in pituitary gland as a result of positive feedback regulation by the elevated estrogen during follicle maturation. The LH surge triggers the release of mature egg from ovarian follicle and the development of remaining follicle into corpus luteum. Progesterone secreted by corpus luteum is needed for preparing the endometrium for egg implantation.
  LH is critical for ovulation in women. In men, LH stimulates testis to produce testosterone. LH has a α subunit that is identical to the one in other glycoprotein hormones such as TSH, FSH and HCG. LH level used for predicating ovulation in women to increase the chance of insemination.
• Synonyms: LHB, LH-B, LSH-beta, Luteinizing hormone subunit beta, Lutropin beta chain, Lutropin subunit beta

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: GnRH signaling pathway, Neuroactive ligand-receptor interaction