TSH beta (TSHB) Mouse Monoclonal Antibody [Clone ID: TSH-2]

CAT#: AM09312HR-N

TSH beta (TSHB) mouse monoclonal antibody, clone TSH-2, HRP

Specifications

Product Data

• Clone Name: TSH-2
• Applications: ELISA
• Recommended Dilution: ELISA: This antibody can be used as Tracer in Sandwich ELISA with our matched anti-TSH Antibody Cat.-No AM09311PU-N (Mouse anti Human TSH monoclonal antibody, Clone TSH-1).
  The suggested tracer concentration is 1/1000 dilution.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human TSH
• Specificity: This antibody is reactive to beta chain of Human TSH
• Formulation: 50% 0.01M PBS, pH 7.2 and 50% Glycerol
  Label: HRP
  State: Liquid purified IgG fraction
• Purification: Affinity Chromatography on Protein G
• Conjugation: HRP
• Storage:

  Store (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: thyroid stimulating hormone beta
• Database Link:
  Entrez Gene 7252 Human
  UniProt ID P01222
• Background: Thyroid stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones.
  TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
• Synonyms: Thyrotropin subunit beta, Thyroid-stimulating hormone subunit beta, TSH, TSHB, TSH beta