Factor VII (F7) Mouse Monoclonal Antibody [Clone ID: RFFVII/2]

CAT#: AM09326PU-N

Factor VII (F7) mouse monoclonal antibody, clone RFFVII/2, Aff - Purified

Specifications

Product Data

• Clone Name: RFFVII/2
• Applications: ELISA, R, WB
• Recommended Dilution: ELISA.
  Clone RFFVII/2 may be used as a Capture antibody in Immunoassay for Factor VII in combination with clone RFFVII/1 as a Detection reagent.
  Radioimmunoassays.
  Western blotting: This Factor VII antibody binds to a conformational epitope and will not bind to reduced Factor VI.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified Factor VII.
• Specificity: Recognizes Human Factor VII antigen. Other spcies not tested.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified IgG fraction from Tissue Culture Supernatant
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens coagulation factor VII (F7), transcript variant 1
• Database Link:
  Entrez Gene 2155 Human
• Background: Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver and having anormal circulating concentration of between 400 and 600 µg/L. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa through cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts Prothrombin to Thrombin.
• Synonyms: Proconvertin, SPCA

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Complement and coagulation cascades