LDHA Mouse Monoclonal Antibody [Clone ID: AT1A4]

CAT#: AM09366PU-N

LDHA mouse monoclonal antibody, clone AT1A4, Purified


USD 340.00

2 Weeks*

Size
    • 100 ul

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Other products for "LDHA"

Specifications

Product Data
Clone Name AT1A4
Applications ELISA, IF, WB
Recommended Dilution ELISA.
Western blot (1/500-1/8000).
Immunofluorescence (1/500-1/8000).
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Recombinant Human LDHA (1-332aa) purified from E. coli
Specificity The antibody recognizes Human LDHA. Other species not tested.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity chromatography on Protein G
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 1
Background Lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc and hypoxia-inducible factor (HIF-1). LDHA expression is repressed by SugR in the absence of sugar. Reduction of LDHA causes bioenergetic and oxidative stress leading to cell death. LDHA (LDH-5, M-LDH, or A4), which is the predominant form in skeletal muscle, kinetically favors the conversion of pyruvate to lactate. Therefore, LDH-A is an attractive target for cancer therapy since its expression is largely relegated to skeletal muscle.
Synonyms LDH-A, L-lactate dehydrogenase A chain, LDH-M, PIG19, NY-REN-59
Reference Data
Protein Families Druggable Genome
Protein Pathways Cysteine and methionine metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.