GAPDH (Loading Control) Mouse Monoclonal Antibody [Clone ID: AT8G4]

CAT#: AM09367PU-N

GAPDH (Loading Control) mouse monoclonal antibody, clone AT8G4, Purified


USD 340.00

2 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Clone Name AT8G4
Applications ELISA, IF, WB
Recommended Dilution ELISA: 1/1000.
Western blot: 1/500-1/10,000.
Immunofluorescence: 1/500-1/10,000.
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Recombinant Human GAPDH (1-335aa) purified from E. coli.
Specificity The antibody recognizes Human GAPDH. Other species not tested.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-G affinity chromatography
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens glyceraldehyde-3-phosphate dehydrogenase (GAPDH), transcript variant 1
Background Multiple roles for glyceraldehyde-3-phosphate dehydrogenase (GAPDH) have been recently appreciated. GAPDH is found in the particulate fractions, such as the nucleus, the mitochondria, and the small vesicular fractions. GAPDH gene expression is specifically increased during programmed neuronal cell death. When cells are exposed to various stressors, dynamic subcellular re-distribution of GAPDH occurs. GAPDH is also involved in various diseases, especially neurodegenerative disorders and cancers. As a membrane protein, GAPDH functions in endocytosis; in the cytoplasm, it is involved in the translational control of gene expression; in the nucleus, it functions in nuclear tRNA export, in DNA replication, and in DNA repair.
Synonyms GAPD, CDABP0047
Reference Data
Protein Families ES Cell Differentiation/IPS
Protein Pathways Alzheimer's disease, Glycolysis / Gluconeogenesis, Metabolic pathways

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.