Aurora B (AURKB) Mouse Monoclonal Antibody [Clone ID: AT2B1]

CAT#: AM09372PU-N

Aurora B (AURKB) mouse monoclonal antibody, clone AT2B1, Purified


USD 340.00

2 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Clone Name AT2B1
Applications ELISA, FC, IF, WB
Recommended Dilution ELISA. 
WesternBlot.

Flow Cytometry.
Immunofluorescence: 1/1000-1/2000.
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Recombinant human Aurora kinase B (1-344aa) purified from E. coli
Specificity The antibody recognizes Human Aurora kinase B. Other species not tested.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration 1.0 mg/ml
Purification Affinity Chromatography on Protein G
Gene Name Homo sapiens aurora kinase B (AURKB), transcript variant 1
Background The aurora family (A, B and C) are serine threonine kinases and key regulators of chromosome segregation during mitosis. Aurora kinase B is a chromosomal passenger protein that regulates chromosome segregation and cytokinesis. Aurora kinase B is associated with the level of genetic instability within tumours and patient survival. It is strongly expressed in exponentially proliferating bronchial epithelial cells in culture and that this expression is markedly reduced in confluent cells. It is also shown that almost all tumours show higher levels of Aurora kinase B expression than their matched normal lung tissues, which could therefore simply be a consequence of a higher proliferative index, or be typical of the progenitor cell and atypical of the bulk of normal lung cells.
Synonyms Aurora-B, Aurora/IPL1-related kinase 2, STK-1, AURKB, AIK2, AIM1, ARK2, STK12
Reference Data
Protein Families Druggable Genome, Protein Kinase, Stem cell - Pluripotency

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.