NRAS (1-186) Mouse Monoclonal Antibody [Clone ID: AT2G9]

CAT#: AM09391PU-S

NRAS (1-186) mouse monoclonal antibody, clone AT2G9, Purified


USD 230.00

2 Weeks*

Size
    • 50 ul

Product Images

Other products for "NRAS"

Specifications

Product Data
Clone Name AT2G9
Applications ELISA, FC, IF, WB
Recommended Dilution ELISA.
Western blot (1:500 - 1:5000; recommended starting dilution is 1:1000).
Immunocytochemistry / Immunoflourescence.
Flow cytometry.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant human NRAS (1-186aa) purified from E. coli
Specificity The antibody recognizes human RAS at aa 1-186. Other species not tested.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-G affinity chromatography
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens neuroblastoma RAS viral oncogene homolog (NRAS)
Background The Ras protein is a subfamily of small GTPases that are involved in signal transduction. They are activated by ligand-binding receptor tyrosine kinases such as EGFR, PDGFR, CSF and FGF. These kinases transiently convert RAS-GDP (inactive form) to RAS-GTP, the active form of RAS. The main genes are HRAS, NRAS and KRAS.
Synonyms NRAS, HRAS1, KRAS, KRAS2, RASK2, HRAS, HRAS1
Reference Data
Protein Families Druggable Genome
Protein Pathways Acute myeloid leukemia, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Chemokine signaling pathway, Chronic myeloid leukemia, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Gap junction, Glioma, GnRH signaling pathway, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway, Thyroid cancer, Tight junction, VEGF signaling pathway

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.