Pyruvate Kinase (PKLR) Mouse Monoclonal Antibody [Clone ID: AT1E3]

CAT#: AM09397PU-N

Pyruvate Kinase (PKLR) mouse monoclonal antibody, clone AT1E3, Purified


USD 340.00

2 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Clone Name AT1E3
Applications ELISA, WB
Recommended Dilution ELISA.
Western blot (1:500).
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant human PKLR (47-574aa) purified from E. coli
Specificity The antibody recognizes human PKLR. Other species not tested.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-G affinity chromatography
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens pyruvate kinase, liver and RBC (PKLR), transcript variant 1
Background PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. The PKLR gene encodes the L- and R-type isoenzymes through alternative splicing events under the control of different promoters. The L-type isoform also exists as a tetramer and is upregulated by glucose with implications in maturity-onset diabetes of the young.
Synonyms PK1, PKL, Pyruvate kinase R/L, Pyruvate kinase 1, R-type/L-type pyruvate kinase, Red cell/liver pyruvate kinase
Reference Data
Protein Families Druggable Genome
Protein Pathways Glycolysis / Gluconeogenesis, Insulin signaling pathway, Maturity onset diabetes of the young, Metabolic pathways, Purine metabolism, Pyruvate metabolism, Type II diabetes mellitus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.