Cytokeratin 8 (KRT8) (+ KRT18) Mouse Monoclonal Antibody [Clone ID: CK207]

CAT#: AM10027BT-N

Cytokeratin 8 (KRT8) (+ KRT18) mouse monoclonal antibody, clone CK207, Biotin, Purified


USD 435.00

2 Weeks*

Size
    • 1 ml

Product Images

Other products for "KRT8"

Specifications

Product Data
Clone Name CK207
Applications IF, IHC
Recommended Dilution Immunohistochemistry.
Immunocytochemistry (Frozen or Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections and cell smears).
For IHC dilute concentared antibody at 1/50-1/100, use streptavidin~biotin system or polymer system, incubate 30 minutes at room temperature. 
For FFPE tissue sections antigen retriever like trypsin or citrate is required.
Citrate antigen retriever: Boil tissue in 10 mM citrate, pH 6.0 for 10-15 minutes followed by cooling for 10-15 minutes at RT.
Biotinylated antibody can be diluted 1/40-1/80 for IHC.
Recommended Positive Control: Human breast, any GI tissue or skin.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified keratins.
Specificity This antibody recognizes all simple epithelia and glandular (thyroid, breast, GI tract, respiratory tract, urinary tract).
Most squamous carcinomas and all adenocarcinomas are stained by this antibody and keratinizing squamous carcinomas are mostly negative.
Cellular Localization: Cytoplasmic.
Formulation PBS, pH 7.4
Label: Biotin
State: Purified
State: Liquid purified Ig fraction
Stabilizer: 1% BSA
Preservative: 0.05% Sodium Azide
Concentration lot specific
Purification Protein A Chromatography
Conjugation Biotin
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: One year from despatch.
Gene Name Homo sapiens keratin 8 (KRT8), transcript variant 2
Background Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1, CK2, CK3, CK4, CK5, CK6, CK7, CK8 and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10, CK12, CK 13, CK14, CK16, CK17, CK18, CK19 and CK20.
Synonyms KRT8, CYK8, Cytokeratin-8, CK8, Keratin-8, K8, Cytokeratin endo A
Reference Data
Protein Families Druggable Genome

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.