CD163

CAT#: AM10062SU-N

Anti CD25 / IL2RA monoclonal antibody, clone4C9, Supernatant

Specifications

Product Data

• Clone Name: 4C9
• Applications: P
• Recommended Dilution: P
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG2b
• Clonality: Monoclonal
• Specificity: Recognizes Human CD25. Other species not tested.
  Cellular Localization: Membrane.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
  Shelf life: one year from despatch.
• Gene Name: CD163 molecule
• Database Link:
  NP_004235
  Entrez Gene 9332 Human
  UniProt ID Q86VB7
• Background: IL-2R (T-cell growth factor receptor) consists of a chain of 55kDa (also known as Tac antigen or p55 or alpha chain) and a p75 or beta chain. IL-2RA is over-expressed on the surface of activated T cells, HTLV-1 or -2 positive T-cell lines, and moderately expressed on activated B-cells, NK-cells, and macrophages. CD25 molecule alone appears to function as a low affinity receptor and associates wtih CD122 (IL-2R beta chain, p75) and CD132 (common gamma chain) to form the high affinity IL-2 receptor complex.
• Synonyms: M130; MM130

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane