Cytokeratin 20 (KRT20) Mouse Monoclonal Antibody [Clone ID: Ks20.8]

CAT#: AM10100SU-N

Cytokeratin 20 (KRT20) mouse monoclonal antibody, clone Ks20.8, Supernatant

Product Images

Formalin-Fixed, Paraffin-Embedded Human colon carcinoma stained with Cytokeratin-20 antibody Cat.-No. AM10100SU-N using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining of carcinoma glands.

Specifications

Product Data

• Clone Name: Ks20.8
• Applications: IHC, WB
• Recommended Dilution: Western Blot.
  Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/50-1/150
  Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended.
  Use Polymer anti Mouse/Rabbit IgG as a detection system.
  Positive Control: Colon carcinoma.
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Semi-purified Human Cytokeratin preparation.
• Specificity: Recognizes Cytokeratin 20.
  Cellular Localization: Cytoplasmic.
• Formulation: State: Supernatant
  State: Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide.
• Gene Name: Homo sapiens keratin 20 (KRT20)
• Database Link:
  Entrez Gene 66809 MouseEntrez Gene 54474 Human
• Background: Keratin 20 / cytokeratin20 (CK20) is a Type-I keratin which is primarily expressed in gastric and intestinal epithelium, urothelium, and Merkel-cells. CK20 is expressed in adenocarcinomas of the colon, stomach, pancreas and the bile system. CK20 is also present in mucinous ovarian tumors, transitional-cell and Merkel-cell carcinomas. Notably, the squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non-mucinous tumors of the ovary, and small cell carcinomas lack in CK20.
• Synonyms: Cytokeratin 20, Keratin-20, KRT20, CK20, K20, Protein IT