MMP9 Rabbit Monoclonal Antibody [Clone ID: EP1255Y]

CAT#: AM10115SU-N

MMP9 rabbit monoclonal antibody, clone EP1255Y, Supernatant

Product Images

Formalin-Fixed, Paraffin-Embedded Human ovarian carcinoma stained with MMP9 antibody Cat.-No. AM10115SU-N using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining of carcinoma cells.

Specifications

Product Data

• Clone Name: EP1255Y
• Applications: IF, IHC, WB
• Recommended Dilution: Western Blot.
  Immunocytochemistry.
  Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/50-1/100
  Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended.
  Use Polymer anti Mouse/Rabbit IgG as a detection system.
  Positive Control: Placenta, or breast carcinoma.
• Reactivities: Guinea Pig, Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues on Human MMP-9
• Specificity: This antibody reacts with both latent and active MMP-9.
  Cellular Localization: Cytoplasmic.
• Formulation: State: Supernatant
  State: Liquid Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide.
• Purification: Affinity Chromatography.
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens microphthalmia-associated transcription factor (MITF), transcript variant 4
• Database Link:
  Entrez Gene 4286 HumanEntrez Gene 4318 Human
• Background: Metallomatrix proteases (MMPs) are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis.
• Synonyms: Matrix metalloproteinase-9, MMP9, 92 kDa type IV collagenase, 92 kDa gelatinase, GELB, Gelatinase B, CLG4B
• Note: Theoretical Molecular Weight: 92kDa

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Melanogenesis, Melanoma, Pathways in cancer