Transglutaminase-2 Mouse Monoclonal Antibody [Clone ID: 7D2]
Specifications
Product Data | |
Clone Name | 7D2 |
Applications | ELISA, IHC, WB |
Recommended Dilution | ELISA. |
Reactivities | Guinea Pig, Human |
Host | Mouse |
Isotype | IgG3 |
Clonality | Monoclonal |
Immunogen | Purifed Transglutaminase 2 from Guinea Pig liver |
Specificity | Reacts with Guinea Pig TGM2 protein. React in liver and blood cells (erythrocytes). Also reacts with recombinant Human tissue Transglutaminase (rh-TGase-2) |
Formulation | 0.1M Tris, 0.1M Glycine and 2% Sucrose State: Purified State: Lyophilized purified antibody Preservative: None |
Reconstitution Method | Restore in distilled water. |
Purification | Affinity Chromatography on Protein A |
Background | Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing. |
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