SOD2 Mouse Monoclonal Antibody [Clone ID: 37CT127.5.11.6]

CAT#: AM11059PU-N

SOD2 Antibody

Product Images

Figure 1. Western blot analysis of anti-SOD2 Monoclonal Antibody by SOD2-GST fusion protein (GST MW=26 kD. SOD2-GST fusion protein (arrow) was detected using the purified Mab. (1:2000).

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  Figure 2. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SOD2 Monoclonal Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Clone Name: 37CT127.5.11.6
• Applications: IHC, WB
• Recommended Dilution: WB 1:2000
  WB 1:2000
  IHC-P 1:10~50
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Immunogen: Purified His-tagged SOD protein (Fragment).
• Specificity: Purified His-tagged SOD protein(Fragment) was used to produced this monoclonal antibody.
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 24750 kDa
• Gene Name: superoxide dismutase 2, mitochondrial
• Database Link:
  NP_000627.2
  Entrez Gene 6648 Human
  UniProt ID P04179
• Background: This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Synonyms: Superoxide dismutase Mn