EGFR Mouse Monoclonal Antibody [Clone ID: 51CT78.40.5]

CAT#: AM11067SU-N

EGFR mouse monoclonal antibody, clone 51CT78.40.5, Ascites

Product Images

Figure 1. Western blot analysis of anti-EGFR Monoclonal Antibody (Cat.#AM11067SU-N) by EGFR recombinant protein (Fragment). EGFR (Fragment) protein (arrow) was detected using the ascites Mab (1:2000).

Specifications

Product Data

• Clone Name: 51CT78.40.5
• Applications: WB
• Recommended Dilution: ELISA: 1/4000.
  Western blotting: 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified His-tagged EGFR protein( Fragment).
• Specificity: This antibody is specific to EGFR.
• Formulation: State: Ascites
  State: Ascites containing 0.09% (W/V) Sodium Azide as preservative.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: epidermal growth factor receptor
• Database Link:
  Entrez Gene 1956 Human
  UniProt ID P00533
• Background: EGFR is a transmembrane glycoprotein that is a member of a family of protein tyrosine kinases crucial in maintaining a normal balance in cell growth and development. A prototype member of the type 1 receptor tyrosine kinases, EGFR is encoded by the cellular oncogene cerbB1. EGFR has an extracellular ligand binding domain, a single transmembrane region, and cytoplasmic domain which is composed of a tyrosine kinase domain and a carboxy terminal domain. The carboxy terminal domain contains at least four tyrosine autophosphorylation sites. Increased production or activation of EGFR has been associated with poor prognosis in a variety of tumors. EGFR overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
• Synonyms: Epidermal growth factor receptor, EGF Receptor, erbB-1, c-ErbB-1