CD162 (SELPLG) Mouse Monoclonal Antibody [Clone ID: TC2]

CAT#: AM12002AC-N

CD162 (SELPLG) mouse monoclonal antibody, clone TC2, APC


USD 300.00

2 Weeks*

Size
    • 100 Tests

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Specifications

Product Data
Clone Name TC2
Applications FC
Recommended Dilution The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 10e6 cells in a suspension.
The content of a vial (1 ml) is sufficient for 100 tests.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human thymocytes
Specificity This antibody reacts with CD162, a 220 kDa type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes; it is also expressed on a subpopulation of B lymphocytes and CD34+ bone marrow cells.
Formulation PBS containing 15 mM Sodium Azide as preservative and 0.2% (w/v) high-grade protease free BSA as a stabilizing agent.
Label: APC
State: Liquid purified Ig fraction
Label: Conjugated to Allophycocyanin
Purification Size-Exclusion Chromatography
Conjugation APC
Storage Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens selectin P ligand (SELPLG), transcript variant 2
Background CD162 (P-selectin glycoprotein ligand-1, PSGL-1) is a sialomucin constitutively expressed as a disulfide-linked homodimer of two 120 kDa subunits on the surface of circulating leukocytes. CD162 serves as a ligand for P- E- and L-selectin, with the highest affinity for P-selectin. It is thus involved in leukocyte rolling at the endothelial surfaces, prerequisite for firm leukocyte adhesion and subsequent transendothelial migration. CD162 also mediates leukocyte-platelet adhesion and interleukocyte contacts. Whereas serving as an adhession molecule on mature leukocytes, CD162 is a potent negative regulator of human hematopoietic progenitors.
Synonyms PSGL-1, Selectin P ligand, SELPLG
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.