CD62L (SELL) Mouse Monoclonal Antibody [Clone ID: DREG56]

CAT#: AM12066FC-N

CD62L (SELL) mouse monoclonal antibody, clone DREG56, FITC


USD 270.00

2 Weeks*

Size
    • 100 Tests

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Specifications

Product Data
Clone Name DREG56
Applications FC
Recommended Dilution Flow cytometry analysis of human blood cells: 20 µl reagent / 100 µl of whole blood or 106 cells in a suspension.
The content of a vial (2 ml) is sufficient for 100 tests.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen PMA-activated human peripheral blood leukocytes
Specificity This antibody detects CD62L / L-selectin, a 65-76 kDa cell surface protein, expressed by neutrophils, monocytes, and subsets of T, B, and NK cells, that interacts with specific carbohydrates exposed on activated endothelial cells.
Formulation Phosphate buffered saline (PBS) solution containing 15mM sodium azide
Label: FITC
State: Liquid purified Ig fraction
Label: Conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.
Conjugation FITC
Storage Store the antibody undiluted at 2 - 8 °C. DO NOT FREEZE!
This antibody is photosensitive and should be protected from light.
Stability Shelf life: One year from despatch.
Gene Name Homo sapiens selectin L (SELL), transcript variant 1
Background CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1). The level of CD62L expression can be used to help distinguish naive T cells from effector/memory T cells.
Synonyms SELL, LNHR, LYAM1, Leu-8, TQ1, gp90-MEL, LECAM1, LAM-1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.