Adenosine Receptor A2a (ADORA2A) (full length) Mouse Monoclonal Antibody [Clone ID: 7F6-G5-A2 / 7F6]

CAT#: AM12133PU-N

Adenosine Receptor A2a (ADORA2A) (full length) mouse monoclonal antibody, clone 7F6-G5-A2 / 7F6, Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Clone Name 7F6-G5-A2 / 7F6
Applications FC, IHC, WB
Recommended Dilution Flow Cytometry.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
IHC-Pfa: 1 µg/ml.
Western Blot: 1/1000.
Reactivities Canine, Guinea Pig, Human, Mouse, Rabbit, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen 6His-tagged full-length Human recombinant A2A receptor. 
3rd Intracellular Domain (SQPLPGER)
Specificity This antibody recognizes Human Adenosine Receptor A2A at ~43 kDa.
Does not recognize Adenosine Receptor A2A in knockout mice.
Formulation 0.01M Tris-Glycine, pH 7.4, 0.15M Sodium Chloride
State: Purified
State: Liquid purified IgG fraction
Preservative: 0.05% Sodium Azide
Concentration lot specific
Purification Protein G Chromatography
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens adenosine A2a receptor (ADORA2A), transcript variant 3
Background The A2a Adenosine Receptor is a major target of caffeine. This receptor inhibits cell aggregation, induces vasodilation, and downregulates inflammation. This gene encodes a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. The encoded protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.
Synonyms ADORA2A, ADORA2
Reference Data
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.