GM CSF Receptor alpha (CSF2RA) Mouse Monoclonal Antibody [Clone ID: 4H1]

CAT#: AM20017RP-N

GM CSF Receptor alpha (CSF2RA) mouse monoclonal antibody, clone 4H1, PE

Product Images

Surface staining (flow cytometry) of human peripheral blood with anti-CD116 (4H1) PE.

Specifications

Product Data

• Clone Name: 4H1
• Applications: FC
• Recommended Dilution: Flow Cytometry analysis of Human blood cells using 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: CD116-transfected COS cells
• Specificity: This antibody recognizes Human CD116, the GM-CSF receptor alpha subunit (approx. 80 kDa) expressed e.g. by neutrophils, eosinophils, monocytes and macrophages.
• Formulation: Phosphate buffered saline (PBS)
  Label: PE
  State: Liquid purified Ig fraction
  Stabilizer: 0.2% (w/v) high-grade protease free BSA
  Preservative: 15 mM Sodium Azide
  Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions
• Purification: The conjugate is purified by Size-Exclusion Chromatography and adjusted for direct use
• Conjugation: PE
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 1438 Human
• Background: CD116 (GM-CSF R alpha) is the low affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF). CD116 heterodimerizes with CD131, the common beta chain subunit shared with IL-3 and IL5 receptors, to form the high affinity GM-CSF receptor. CD116 is expressed by myeloid cells including macrophages, neutrophils, eosinophils, dendritic cells, and their precursors, as well as on endothelial cells. It is being used as a specific marker of myeloid leukemias.
• Synonyms: GM-CSF-R-alpha, GMR, CSF2R, CSF2RY, GMCSF Receptor alpha, GM-CSF Receptor alpha