C Reactive Protein (CRP) Mouse Monoclonal Antibody [Clone ID: C2]

CAT#: AM20203PU-N

C Reactive Protein (CRP) mouse monoclonal antibody, clone C2, Aff - Purified

Specifications

Product Data

• Clone Name: C2
• Applications: ELISA
• Recommended Dilution: ELISA: The antibody C2 has been tested as the Capture antibody in a Sandwich ELISA for analysis of Human C-Reactive Protein in combination with the antibody C6 (AM20204PU-N).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified human CRP
• Specificity: The antibody C2 recognizes Human CRP, an 117 kDa plasma acute phase protein.
  It recognizes the antigen both in the presence and in the absence (samples containing EDTA) of Ca2+.
• Formulation: Phosphate buffered saline (PBS), pH~7.4 with 15 mM Sodium Azide as preservative.
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein-A.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens C-reactive protein, pentraxin-related (CRP), transcript variant 2
• Database Link:
  Entrez Gene 1401 Human
• Background: The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein compound of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa; physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease.
• Synonyms: PTX1, C Reactive Protein, Pentraxin-related

Reference Data

• Protein Families: Secreted Protein