Flt4 Rat Monoclonal Antibody [Clone ID: 7A3]

CAT#: AM20378PU-N

Flt4 rat monoclonal antibody, clone 7A3, Purified


USD 365.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name 7A3
Applications IF, WB
Recommended Dilution Western Blot: 1-5 µg/ml.
Immunofluorescence: 2-10 µg/ml.
Reactivities Mouse
Host Rat
Isotype IgG1
Clonality Monoclonal
Immunogen Purified, insect cell-derived recombinant Mouse soluble FLT-4 (120 kDa).
Specificity This antibody will detect Mouse VEGFR-3/FLT-4 in Western Blot in PAEC/FLT-4 cells.
Formulation PBS pH 7.4 without preservatives
State: Purified
State: Lyophilized purified IgG fraction
Stabilizer: None
Reconstitution Method Restore in sterile water to a concentration of 0.1-1.0 mg/ml
Purification Protein G Chromatography
Gene Name Mus musculus FMS-like tyrosine kinase 4 (Flt4)
Background Mature native mouse VEGF Receptor 3 (Flt4) is composed of a 751 amino acid residue extracellular domain, a 22 amino acid residue transmembrane domain, and a 565 amino acid residue cytoplasmic domain. Recombinant mature mouse VEGF Receptor 3/Fc is a disulfidelinked dimeric protein. Based on N-terminal sequencing, recombinant mouse VEGF Receptor 3/Fc has Met 17 at the amino-terminus. The amino acid sequence of mouse VEGF Receptor 3 is 88 % identical to human VEGF Receptor 3. VEGF Receptor 3 is a specific marker for lymphatic vessels. In adults, VEGF Receptor 3 expression is restricted to endothelial cells of the lymphatic vessels. It has also been detected on some high endothelial venules, in embryonic prelymphatic blood vessels, in some tumor blood vessels, and in certain hematopoietic and leukemia cells. The predominant role of VEGF Receptor 3 is its involvement in the development of the lymphatic vessel system. Both VEGFC and VEGFD bind and activate the receptors, VEGF Receptor 3 and VEGF Receptor 2.
Synonyms VEGFR3, FLT4, VEGF Receptor 3
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.