ATP2A1 (522-613) Mouse Monoclonal Antibody [Clone ID: 1B11]

CAT#: AM20402PU-N

ATP2A1 (522-613) mouse monoclonal antibody, clone 1B11, Purified

Product Images

Western Blot analysis of ATP2A1 expression in transfected 293T cell line by ATP2A1 monoclonal antibody (clone 1B11).

• 

  Western Blot analysis of ATP2A1 expression in A-431 by ATP2A1 monoclonal antibody (clone 1B11).

• 

  Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)

• 

  Human Skeletal muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)

• 

  Immunofluorescence of monoclonal ATP2A1 antibody on A-431 cell at 10 ug/ml.

Show all 5 images

Specifications

Product Data

• Clone Name: 1B11
• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA: 2.5 µg/ml.
  Immunofluorescence: 10 µg/ml.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: ATP2A1 (NP_775293, 522 a.a. ~613 a.a) partial recombinant protein with GST tag.
• Specificity: This antibody recognizes ATP2A1 at aa 522-613.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: 0.5 mg/ml
• Purification: Protein A Chromatography
• Gene Name: Homo sapiens ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 (ATP2A1), transcript variant b
• Database Link:
  Entrez Gene 487 Human
• Background: The antigen is purified rabbit skeletal muscle sarcoplasmic reticulum. ATP dependent calcium pumps are responsible, in part, for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium ATPases (SERCA). The SERCA1 gene is exclusively expressed in type II (fast) skeletal muscle. The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific form expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. The SERCA3 gene is not as well characterized and is found in non-muscle cells.
• Synonyms: Calcium pump 1 ATPase

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Alzheimer's disease, Calcium signaling pathway