Eph receptor A2 (EPHA2) Mouse Monoclonal Antibody [Clone ID: 1B3C7]

CAT#: AM20406SU-N

Eph receptor A2 (EPHA2) mouse monoclonal antibody, clone 1B3C7, Ascites

Product Images

Western blot analysis using anti-Human EphA2 monoclonal antiobdy against NIH3T3 cell lysate.

• 

  Small intestine, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

• 

  Skin, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 1B3C7
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/10000.
  Immunohistochemistry on Paraffin Sections: 1/200 - 1/400.
  Western Blot: 1/500 - 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of EphA2 expressed in E. Coli.
• Specificity: Recognizes Ephrin Type A Receptor 2 (EPHA2).
• Formulation: State: Ascites
  State: Ascites fluid containing 0.03% Sodium Azide as preservative.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens EPH receptor A2 (EPHA2)
• Database Link:
  Entrez Gene 1969 Human
• Background: The Eph family of receptors is the largest known subfamily of receptor tyrosine kinases (RTK). Eph RTKs and their ligands, the ephrins, are frequently overexpressed in a variety of cancers and tumor cell lines. One Eph family member, EphA2, is also overexpressed in a wide variety of cancers, including breast, small-cell lung and gastrointestinal cancers, melanomas, and neuroblastomas. The ephrin-Eph interactions are important in development, especially in cell-cell interactions involved in nervous system patterning and possibly in cancer.
• Synonyms: Ephrin type-A receptor 2, Epithelial cell kinase, Eph receptor A2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Axon guidance