Fibrinogen beta chain (FGB) (30-300) Mouse Monoclonal Antibody [Clone ID: 1F9]

CAT#: AM20416SU-N

Fibrinogen beta chain (FGB) (30-300) mouse monoclonal antibody, clone 1F9, Ascites

Product Images

Western blot analysis using Monoclonal anti-FGB antibody against human plasma (Lane 1).

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  Liver, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Uterus, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 1F9
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/10000.
  Immunohistochemistry on Paraffin Sections: 1/200 - 1/300.
  Western Blot: 1/500 - 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant protein encoding amino acids 30-300 of Human FGB.
• Specificity: Recognizes Fibrinogen Beta Chain (FGB).
• Formulation: State: Ascites
  State: Ascites fluid containing 0.03% Sodium Azide as preservative.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens fibrinogen beta chain (FGB), transcript variant 1
• Database Link:
  Entrez Gene 2244 Human
• Background: FIBB is the beta component of Fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
• Synonyms: FGB, FIBB

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades