MCK10 (DDR1) Mouse Monoclonal Antibody [Clone ID: 2G4E12]

CAT#: AM20432SU-N

MCK10 (DDR1) mouse monoclonal antibody, clone 2G4E12, Ascites

Product Images

Western blot analysis using CD167a / DDR1 antibody Cat.-No AM20432SU-N against truncated MBP-DDR1 recombinant protein (Lane 1).

• 

  Formalin-Fixed, Paraffin-Embedded Human Kidney stained with CD167a / DDR1 antibody Cat.-No AM20432SU-N.

• 

  Formalin-Fixed, Paraffin-Embedded Human Testis stained with CD167a / DDR1 antibody Cat.-No AM20432SU-N.

Specifications

Product Data

• Clone Name: 2G4E12
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/10000.
  Immunohistochemistry on Paraffin Sections: 1/200 - 1/300.
  Western Blot: 1/500 - 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified Recombinant fragment of DDR1 (aa 602-681) expressed in E.coli
• Specificity: Recognizes Human Discoidin Domain Receptor (DDR1).
• Formulation: State: Ascites
  State: Ascites fluid
  Preservative: 0.03% Sodium Azide
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens discoidin domain receptor tyrosine kinase 1 (DDR1), transcript variant 1
• Database Link:
  Entrez Gene 780 Human
• Background: DDR1 is a DDR/TKT type protein kinase. DDR1 is activated by various types of collagen, including types I through IV. Binding of collagen to DDR1 protein results in autophosphorylation and a delayed but sustained tyrosine kinase activation. DDR1 may function in cell-to-cell interaction or recognition. At least three mRNA variants, resulting in different protein isoforms of 875, 913 and 919 amino acids, have been reported. DDR1 protein has been shown to be over expressed in human breast, ovarian, esophageal and pediatric brain tumors.
• Synonyms: Tyrosine kinase DDR-1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE, MCK10, Epithelial discoidin domain receptor 1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane