PPAR gamma (PPARG) (170-270) Mouse Monoclonal Antibody [Clone ID: 3A4A9, 1E6A1]

CAT#: AM20438SU-N

PPAR gamma (PPARG) (170-270) mouse monoclonal antibody, clone 3A4A9, 1E6A1, Ascites

Product Images

Western blot analysis using PPARG antibody Cat.-No [AM20438PU-N] against truncated PPARG-His recombinant protein (Lane 1) and full-length PPARG (aa1-477) transfected CHO-K1 cell lysate (Lane 2).

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  Formalin-Fixed, Paraffin-Embedded Human Adrenal stained with PPARG antibody Cat.-No [AM20438PU-N] at 1/200 dilution after heat-induced antigen retrieval.

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  Formalin-Fixed, Paraffin-Embedded Human Prostate stained with PPARG antibody Cat.-No [AM20438PU-N] at 1/200 dilution after heat-induced antigen retrieval.

Specifications

Product Data

• Clone Name: 3A4A9, 1E6A1
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/10000.
  Immunohistochemistry on Paraffin Sections: 1/200 - 1/400.
  Western Blot: 1/500 - 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of PPARG (aa170-270) expressed in E. Coli.
• Specificity: Recognizes Peroxisome Proliferator-Activated Receptor Gamma (PPARG).
• Formulation: State: Ascites
  State: Ascites fluid containing 0.03% Sodium Azide as preservative
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens peroxisome proliferator activated receptor gamma (PPARG), transcript variant 2
• Database Link:
  Entrez Gene 5468 Human
• Background: Peroxisome proliferator-activated receptor gamma (PPARG). This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
• Synonyms: PPARG, NR1C3

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Protein Pathways: Huntington's disease, Pathways in cancer, PPAR signaling pathway, Thyroid cancer