Calnexin (CANX) Mouse Monoclonal Antibody [Clone ID: 3H4A7]

CAT#: AM20453SU-N

Calnexin (CANX) mouse monoclonal antibody, clone 3H4A7, Ascites

Product Images

Western blot analysis using Monoclonal anti-Calnexin antibody against A431 (Lane 1), Hela (Lane 2), MCF-7 (Lane 3) and A549 (Lane 4) cell lysate.

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  Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Prostate, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Spleen, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Thyroid, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

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Specifications

Product Data

• Clone Name: 3H4A7
• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA: 1/10000.
  Immunofluorescence: 1/200 - 1/1000.
  Immunohistochemistry on Paraffin Sections: 1/200 - 1/400.
  Western Blot: 1/500 - 1/2000.
• Reactivities: Bovine, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Synthetic peptide - KLH conjugated - of Human Calnexin
• Specificity: Recognizes Calnexin (CANX).
• Formulation: State: Ascites
  State: Ascites fluid containing 0.03% Sodium Azide as preservative
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens calnexin (CANX), transcript variant 2
• Database Link:
  Entrez Gene 12330 MouseEntrez Gene 29144 RatEntrez Gene 704794 MonkeyEntrez Gene 821 Human
• Background: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
• Synonyms: IP90, p90, CANX, ER Marker

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Antigen processing and presentation