NM23A (NME1) Mouse Monoclonal Antibody [Clone ID: 4B2]

CAT#: AM20457SU-N

NM23A (NME1) mouse monoclonal antibody, clone 4B2, Ascites

Product Images

Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 4B2
• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.
  Immunofluorescence: 1/200 - 1/1000.
  Immunohistochemistry on Paraffin Sections: 1/200.
  Western Blot: 1/500 - 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant Human NME1 protein.
• Specificity: Recognizes Non-metastatic Cells 1 (NM23A/NME1).
• Formulation: State: Ascites
  State: Ascites fluid containing 0.03% Sodium Azide as preservative
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens NME/NM23 nucleoside diphosphate kinase 1 (NME1), transcript variant 2
• Database Link:
  Entrez Gene 4830 Human
• Background: Nucleoside diphosphate kinase A, also called NME1 (Non-metastatic cells 1), is expressed in different tumor types where their levels have been alternatively associated with reduced or increased metastatic potential. Reductions in NME1 expression have been significantly associated with aggressive behavior in melanoma, breast, colon, and gastric carcinomas. On the contrary, high levels of NME1 gene expression are noted in the advanced stage of thyroid carcinomas.
• Synonyms: NME1, NDPKA, NM23, nm23-H1, GAAD

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Metabolic pathways, Purine metabolism, Pyrimidine metabolism