Cytokeratin 18 (KRT18) (391-483) Mouse Monoclonal Antibody [Clone ID: 4D11E4]

CAT#: AM20460SU-N

Cytokeratin 18 (KRT18) (391-483) mouse monoclonal antibody, clone 4D11E4, Ascites

Product Images

Western blot analysis using monoclonal anti-CK18 antibody against Hela (Lane 1), NIH/3T3 (Lane 2), A549 (Lane 3), Jurkat (Lane 4), MCF-7 (Lane 5), HepG2 (Lane 6), A431 (Lane 7), HEK293 (Lane 8) and K562 (Lane 9) cell lysate.

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  Kidney, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 4D11E4
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/10000.
  Immunohistochemistry on Paraffin Sections: 1/200 - 1/400.
  Western Blot: 1/500 - 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant protein encoding amino acids 391-483 of Human KRT18.
• Specificity: Recognizes Cytoskeletal 18 (KRT18).
• Formulation: State: Ascites
  State: Ascites fluid containing 0.03% Sodium Azide as preservative
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens keratin 18, type I (KRT18), transcript variant 1
• Database Link:
  Entrez Gene 3875 Human
• Background: Cytokeratin 18, also known as CK18, CYK18, KRT18. Entrez Protein NP_000215. It encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
• Synonyms: Cytokeratin-18, CK18, Keratin-18, Keratin 18, KRT18, CYK18, K18

Reference Data

• Protein Pathways: Pathogenic Escherichia coli infection