CD1 (CD1D) Mouse Monoclonal Antibody [Clone ID: 51.1]

CAT#: AM20466PU-N

CD1 (CD1D) mouse monoclonal antibody, clone 51.1, Aff - Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Clone Name 51.1
Applications FC, IHC
Recommended Dilution Flow Cytometry.
Immunohistochemistry on Frozen Sections.
Immunohistochemistry on Paraffin Sections: 20 µg/ml.
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human CD1d
Specificity The monoclonal antibody reacts with Human CD1d.
Formulation PBS, pH 7.2 containing < / = 0.09% Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified IgG fraction
Concentration lot specific
Purification Affinity Chromatography
Storage Store the antibody at 2-8°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens CD1d molecule (CD1D), transcript variant 1
Background Human CD1d, a member of the CD1 family with similarity to the non-polymorphic MHC Class I-like molecules. CD1d is a highly conserved single transmembrane receptor of the Immunoglobulin Superfamily. CD1d can associate with beta-microglobulin another feature showing similarity to MHC class I molecules, but can also exist as a nonglycosylated protein not in association with beta microglobulin. This suggests different control mechanisms for presenting glycolipid containing molecules to CD1d reactive NKT cells. Expression of CD1d is found on B cells of the periphery, in resting monocytes and cortical thymocytes. On intestinal epithelial cells (IEC) expression is polarized. Expression can also be found at low levels intracellularly in hepatocytes. In HCV (hepatitis C virus) livers, CD1d is highly expressed compared to normal controls.
Synonyms R3G1
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Hematopoietic cell lineage

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.