C5R1 (C5AR1) Mouse Monoclonal Antibody [Clone ID: 3H1738]
Other products for "C5AR1"
Specifications
Product Data | |
Clone Name | 3H1738 |
Applications | FC, FN, IHC, NEUT |
Recommended Dilution | Flow Cytometry: 1/50. Func. Immunohistochemistry on Paraffin Sections: 10 µg/ml. Neut. |
Reactivities | Human, Rabbit |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | C5AR - peptide: Met1 - Asn31. |
Specificity | Recognizes the C5a receptor (C5aR) CD88, which is predominantly expressed on cells of the myeloid lineage.
Clone 3H1738 was raised against a synthetic peptide Met1 -Asn31 and has recently been shown to recognize the heptameric peptide (D15DKDTLD21). Clone 3H1738 inhibits C5a binding to its receptor. |
Formulation | PBS State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Ion Exchange Chromatography |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens complement C5a receptor 1 (C5AR1) |
Database Link | |
Background | C5a Anaphylatoxin Receptor mediates the effects of one of the most potent chemotactic agents known, in a wide variety of inflammatory cell types. C5a receptor 1 has been implicated in asthma. |
Synonyms | C5a-R, C5aR, C5AR1, Complement Component 5a Receptor 1 |
Reference Data | |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Complement and coagulation cascades, Neuroactive ligand-receptor interaction |
Documents
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