GFAP (Cytopl. dom.) Mouse Monoclonal Antibody [Clone ID: n.n]

CAT#: AM20491PU-N

GFAP (Cytopl. dom.) mouse monoclonal antibody, clone n.n, Purified

Product Images

GFAP antibody staining of Formalin-Fixed, Paraffin-Embedded Human Brain at 1-2 ug/ml followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Clone Name: n.n
• Applications: IF, IHC, IP, WB
• Recommended Dilution: Immunofluorescence.
  Immunohistochemistry on Paraffin Sections: 1 - 2 µg/ml.
  Immunoprecipitation: 2 µg/tst.
  Western Blot: 1 - 2 µg/ml.
• Reactivities: Chicken, Human, Porcine, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: GFAP antibody was raised against porcine spinal cord. Cellular Localization: Cytoplasmic.
• Specificity: Recognizes Porcine Glial Fibrillary Acidic Protein (GFAP) at 51-52kD.
• Formulation: PBS, pH 7.4 containing 0.2% BSA, 0.09% Sodium Azide and 40% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein G Chromatography
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens glial fibrillary acidic protein (GFAP), transcript variant 2
• Database Link:
  Entrez Gene 24387 RatEntrez Gene 2670 Human
• Background: Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
• Synonyms: Glial Fibrillary Acidic Protein

Reference Data

• Protein Families: ES Cell Differentiation/IPS