Caldesmon (CALD1) (smooth) Mouse Monoclonal Antibody [Clone ID: CD-7]

CAT#: AM20595PU-N

Caldesmon (CALD1) (smooth) mouse monoclonal antibody, clone CD-7, Aff - Purified

Specifications

Product Data

• Clone Name: CD-7
• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1 - 2 μg/ml.
  Immunohistochemistry on frozen and paraffin sections: 2 - 4 μg/ml.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Caldesmon from turkey gizzard
• Specificity: This antibody reacts to Caldesmon (smooth).
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Aff - Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens caldesmon 1 (CALD1), transcript variant 2
• Database Link:
  Entrez Gene 800 Human
• Background: Caldesmon is a potential actomyosin regulatory protein found in smooth muscle and nonmuscle cells.The predicted smooth-muscle polypeptide is 793 amino acids long. The high molecular weight caldesmon (h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon (l-CaD) is widely distributed in nonmuscle tissues and cells. Hayashi et al. (1992) demonstrated that the human CDM gene is composed of 14 exons.
• Synonyms: CALD1, CAD, CDM

Reference Data

• Protein Pathways: Vascular smooth muscle contraction