Calcineurin A (PPP3CA) Mouse Monoclonal Antibody [Clone ID: CC-6]

CAT#: AM20596PU-N

Calcineurin A (PPP3CA) mouse monoclonal antibody, clone CC-6, Aff - Purified


USD 405.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name CC-6
Applications IHC, WB
Recommended Dilution Western Blot: 0.25 - 0.5 μg/ml.
Immunohistochemistry on paraffin sections: 0.5 - 1 μg/ml
Reactivities Human, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Bovine brain calcineurin
Specificity This antibody reacts to PPP3CA.
Formulation 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
State: Aff - Purified
State: Lyphilized purified Ig fraction
Reconstitution Method Restore with 1.2% sodium acetate or neutral PBS.
Concentration lot specific
Purification Affinity chromatography
Storage Prior to reconstitution store at -20°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1
Background Calcineurin, the Ca(2+)/calmodulin-regulated protein phosphatase, first detected in skeletal muscle and brain, has been found in all cells from yeast to mammals. Calcineurin A alpha (PPP3CA),is located on human chromosomes 4, Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit. Calcineurin regulates bone formation by the osteoblast.
Synonyms CALNA, CNA, PP2B catalytic subunit, protein phosphatase 2B catalytic subunit alpha
Reference Data
Protein Families Druggable Genome, Phosphatase
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Axon guidance, B cell receptor signaling pathway, Calcium signaling pathway, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.