Calcineurin A (PPP3CA) Mouse Monoclonal Antibody [Clone ID: CC-6]

CAT#: AM20596PU-N

Calcineurin A (PPP3CA) mouse monoclonal antibody, clone CC-6, Aff - Purified

Product Images

Lane 1: Rat brain tissue lysate Lane 2: Rat brain tissue lysate Lane 3: Rat medulla oblongata tissue lysate

Specifications

Product Data

• Clone Name: CC-6
• Applications: IHC, WB
• Recommended Dilution: Western Blot: 0.25 - 0.5 μg/ml.
  Immunohistochemistry on paraffin sections: 0.5 - 1 μg/ml
• Reactivities: Human, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Bovine brain calcineurin
• Specificity: This antibody reacts to PPP3CA.
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Aff - Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS.
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1
• Database Link:
  Entrez Gene 24674 RatEntrez Gene 5530 Human
• Background: Calcineurin, the Ca(2+)/calmodulin-regulated protein phosphatase, first detected in skeletal muscle and brain, has been found in all cells from yeast to mammals. Calcineurin A alpha (PPP3CA),is located on human chromosomes 4, Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit. Calcineurin regulates bone formation by the osteoblast.
• Synonyms: CALNA, CNA, PP2B catalytic subunit, protein phosphatase 2B catalytic subunit alpha

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Axon guidance, B cell receptor signaling pathway, Calcium signaling pathway, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway