GJB1 Mouse Monoclonal Antibody [Clone ID: CXN-32]

CAT#: AM20614PU-N

GJB1 mouse monoclonal antibody, clone CXN-32, Purified

Specifications

Product Data

• Clone Name: CXN-32
• Applications: IHC, WB
• Recommended Dilution: Western Blot: 0.5 - 1 μg/ml.
  Immunohistochemistry on frozen sections: 1 - 2 μg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic connexin-32 peptide (amino acids 105-123) conjugated to KLH.
• Specificity: This antibody reacts to GJB1 / Cx32.
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens gap junction protein beta 1 (GJB1), transcript variant 2
• Database Link:
  Entrez Gene 14618 MouseEntrez Gene 29584 RatEntrez Gene 2705 Human
• Background: Connexin32(CX32), also known as GAP junction protein beta-1(GJB1). Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. CX32 expressed in liver and peripheral nerve. CX32 gene is mapped to Xp11-q13 and is directly regulated by the transcription factor SOX10.
• Synonyms: Gap junction beta-1 protein, Connexin-32

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane