Gelsolin (GSN) Mouse Monoclonal Antibody [Clone ID: GEL-42]

CAT#: AM20623PU-N

Gelsolin (GSN) mouse monoclonal antibody, clone GEL-42, Purified

Specifications

Product Data

• Clone Name: GEL-42
• Applications: IHC, WB
• Recommended Dilution: Western Blot: 0.5 - 1 μg/ml.
  Immunohistochemistry on frozen and paraffin secitions: 1 - 2 μg/ml.
• Reactivities: Human, Rabbit
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human plasma gelsolin.
• Specificity: This antibody reacts to Gelsolin.
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS.
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens gelsolin (GSN), transcript variant 1
• Database Link:
  Entrez Gene 2934 Human
• Background: GAP43 is expressed by developing and regenerating neurons, and to a lesser extent, reactive glial cells.It is used widely to specifically label injured neurons and to score neuronal regeneration. GAP43 is also a neuronal growth cone protein thought to be involved in pathfinding. GAP43 is considered to be a crucial component of an effective regenerative response in the nervous system.
• Synonyms: Brevin, AGEL, GSN

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton